Immunity to Ocular and Genital Herpes Simplex Viruses Infections

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Immunity to Ocular and Genital Herpes Simplex Viruses Infections

1 Pathology and Clinical Laboratory Medicine, Department of Immunology, King Fahad Medical City, Riyadh 11525, Saudi Arabia 2Laboratory of Cellular and Molecular Immunology, Gavin Herbert Eye Institute, College of Medicine, University of California, Irvine, CA 92697-4375, USA 3 INSERM U 1058, Université Montpellier 1, 34090 Montpellier, France 4Department of Pathology andMolecular Medicine, McM...

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Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections

Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2) are amongst the most common human infectious viral pathogens capable of causing serious clinical diseases at every stage of life, from fatal disseminated disease in newborns to cold sores genital ulcerations and blinding eye disease. Primary mucocutaneous infection with HSV-1 & HSV-2 is followed by a lifelong viral latency in the sensor...

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Rapid diagnosis of ocular herpes simplex infections.

BACKGROUND The Surecell herpes (HSV) test kit is a test for detecting the presence of herpes simplex viral antigen by means of a monoclonal antibody based immunoassay. The test has proved to be highly sensitive and specific in diagnosing genital, oral, and dermatological herpes infections. METHODS In this study, samples from patients with ocular keratitis were evaluated by tissue cultures and...

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Ocular herpes simplex.

H.erpesvirus hominis is a highly successful parasite, having developed a relationship to the host which assures its perpetuation without seriously disturbing the host population. From 50 to 90 per cent of the adult population has neutralizing antibodies to herpes simplex, indicating previous infection, but most of these affected individuals show no clinical manifestation of disease. Ocular herp...

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Tzanck smears in herpes simplex virus infections

Background: The diagnosis of herpes simplex virus may requirevirological confirmation. Tzanck smear is an old, rapid, costeffective but nonspecific method that has been recently re-evaluatedas a method for the diagnosis of herpes virus infection. This studywas conducted to compare Tzanck smear and viral culture in thediagnosis of herpes simplex virus infection in patients clinicallysuspected to...

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ژورنال

عنوان ژورنال: Clinical and Developmental Immunology

سال: 2012

ISSN: 1740-2522,1740-2530

DOI: 10.1155/2012/732546